ImmunologybioRxiv
The cIAP ubiquitin ligases sustain type 3 γδ T and innate lymphoid cells during aging to allow normal cutaneous and mucosal responses
J. Rizk, U. M. Morbe, R. Agerholm…·V. Bekiaris
This study shows that cIAP1/2 ubiquitin ligases are essential in early life for maintaining IL-17-producing γδT17 and ILC3 cells, which are critical for immune responses during aging.
DOI 10.1084/jem.20221534