Cell BiologybioRxiv
Zinc intoxication of Mycobacterium marinum during Dictyostelium discoideum infection is counteracted by induction of the pathogen Zn2+ exporter CtpC
L. H. Lefrancois, V. Kalinina, E. Cardenal-Munoz…·C. Barisch
This study shows that M. marinum infection induces Zn2+ accumulation in D. discoideum phagosomes, which is counteracted by bacterial upregulation of the Zn2+ exporter CtpC.
DOI 10.1128/mbio.01313-20