Author

F. Leuba

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:Drosophila· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

T. Soldati· 5 shared N. Hanna· 3 shared C. Barisch· 2 shared C. Bosmani· 2 shared M. Hagedorn· 2 shared A. Gueho· 1 shared A. Luscher· 1 shared A. Palma· 1 shared

Activity by Year

2018-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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5 shared papersCell Biology

T. Soldati

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5 papers

Recent·Most cited

Disruption of vacuolin microdomains in the host Dictyostelium discoideum increases resistance to Mycobacterium marinum-induced membrane damage and infection

C. Bosmani, A. Perret, F. Leuba, A. Gueho, N. Hanna, T. Soldati

The paper shows that disrupting vacuolin microdomains in Dictyostelium discoideum reduces susceptibility to Mycobacterium marinum infection by impairing membrane damage and pathogen escape.

bioRxiv · Nov 16, 2021 · PreprintMicrobiology

Lowe Syndrome-linked endocytic adaptors direct membrane cycling kinetics with OCRL in Dictyostelium discoideum.

A. Luscher, F. Fröhlich, C. Barisch, C. Littlewood, J. Metcalfe, F. Leuba, A. Palma, M. Pirruccello, G. Cesareni, M. Stagi, T. C. Walther, T. Soldati, P. De Camilli, L. E. Swan

This study identifies F&H peptide-containing proteins that interact with OCRL/Dd5P4 in Dictyostelium discoideum, revealing their role in endocytic membrane cycling and potential involvement in Lowe Syndrome phenotypes.

bioRxiv · Apr 24, 2019Cell Biology

Dictyostelium discoideum flotillin homologues are essential for phagocytosis and participate in plasma membrane recycling and lysosome biogenesis

C. Bosmani, F. Bach, F. Leuba, N. Hanna, F. Burdet, M. Pagni, M. Hagedorn, T. Soldati

This study identifies vacuolins in Dictyostelium discoideum as functional homologues of flotillins, essential for phagocytosis, membrane recycling, and lysosome biogenesis.

bioRxiv · Mar 19, 2019Cell Biology

Zinc intoxication of Mycobacterium marinum during Dictyostelium discoideum infection is counteracted by induction of the pathogen Zn2+ exporter CtpC

L. H. Lefrancois, V. Kalinina, E. Cardenal-Munoz, N. Hanna, H. Koliwer-Brandl, J. Appiah, F. Leuba, H. Hilbi, T. Soldati, C. Barisch

This study shows that M. marinum infection induces Zn2+ accumulation in D. discoideum phagosomes, which is counteracted by bacterial upregulation of the Zn2+ exporter CtpC.

bioRxiv · Mar 15, 2019Cell Biology

ESCRT and autophagy cooperate to repair ESX-1-dependent damage to the Mycobacterium-containing vacuole

A. T. Lopez-Jimenez, E. Cardenal Munoz, F. Leuba, L. Gerstenmaier, M. Hagedorn, J. S. King, T. Soldati

The paper shows that ESCRT and autophagy work together to repair damage to the Mycobacterium-containing vacuole caused by ESX-1, preventing bacterial escape.

bioRxiv · May 30, 2018Microbiology