Structural basis for adhesion G protein-coupled receptor Gpr126 function
K. Leon, R. Cunningham, J. Riback, E. Feldman, J. Li, T. Sosnick, M. Zhao, K. Monk, D. Arac
This study determines the structure of the zebrafish Gpr126 ECR, revealing a closed conformation stabilized by alternative splicing and a calcium-binding site, and shows how these features regulate receptor function.
bioRxiv · Oct 17, 2019Biochemistry