Large clones of pre-existing T cells drive early immunity against SARS-COV-2 and LCMV infection.
M. Milighetti, Y. Peng, C. C. S. Tan, M. Mark, G. Nageswaran, S. Byrne, T. Ronel, T. Peacock, A. Mayer, A. Chandran, J. Rosenheim, M. Wheelan, X. Yao, G. Liu, S. L. Felce, , B. Chain
The paper identifies high frequency naive T cell precursors that drive rapid T cell responses during early SARS-COV-2 and LCMV infections.
bioRxiv · Nov 8, 2022Immunology