Author

M. Mark

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Assay:CITE-seq· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

S. Reich-Zeliger· 3 shared B. Chain· 2 shared E. Greenstein· 2 shared N. Friedman· 2 shared A. Chandran· 1 shared A. J. Mentzer· 1 shared A. Madi· 1 shared A. Mayer· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersImmunology

S. Reich-Zeliger

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Multimodal profiling reveals tissue-directed signatures of human immune cells altered with age

S. B. Wells, D. Rainbow, M. Mark, P. P. A. S. Szabo, C. Ergen, A. R. Maceiras, D. P. Caron, E. Rahmani, E. Benuck, V. V. P. Amiri, D. Chen, A. Wagner, S. K. Howlett, L. B. Jarvis, K. L. Elli, , N. Yosef

The paper profiles immune cell RNA and protein expression across tissues and age to identify tissue-specific and age-related immune signatures.

Nature Immunology · Aug 13, 2025Peer-reviewedImmunology

A dominant role of TGFβ in regulating T-cell size and physiology

I. Eizenberg-Magar, J. Rimer, S. Miller, Y. Elyahu, M. Mark, Z. Porat, S. Reich-Zeliger, A. Monsonego, Y. E. Antebi, N. Friedman

This study shows TGFβ profoundly regulates T-cell size and physiology by modulating gene expression and transcription factor networks, independent of other cytokines.

bioRxiv · Jun 2, 2024 · PreprintImmunology

Large clones of pre-existing T cells drive early immunity against SARS-COV-2 and LCMV infection.

M. Milighetti, Y. Peng, C. C. S. Tan, M. Mark, G. Nageswaran, S. Byrne, T. Ronel, T. Peacock, A. Mayer, A. Chandran, J. Rosenheim, M. Wheelan, X. Yao, G. Liu, S. L. Felce, , B. Chain

The paper identifies high frequency naive T cell precursors that drive rapid T cell responses during early SARS-COV-2 and LCMV infections.

bioRxiv · Nov 8, 2022Immunology

Ubiquitination occurs in the mitochondrial matrix byeclipsed targeted components of the ubiquitin machinery

Y. Zhang, O. Karmon, K. Das, M. Mark, N. Lehming, O. Pines

The paper demonstrates that ubiquitination occurs in yeast mitochondrial matrix using components of the ubiquitin machinery, independent of cytosolic proteasome activity.

bioRxiv · Apr 21, 2022Cell Biology

Antigen experience relaxes the organisational structure of the T cell receptor repertoire

M. Mark, S. Reich-Zeliger, E. Greenstein, D. Reshef, A. Madi, B. Chain, N. Friedman

The paper examines how antigen exposure affects the structural organization of T cell receptor repertoires in mice across different life stages and infection states.

bioRxiv · Oct 26, 2021 · PreprintImmunology