E. Haswell

Unbiased proteomic and forward genetic screens reveal that mechanosensitive ion channel MSL10 functions at ER-plasma membrane contact sites in Arabidopsis thaliana

The paper identifies MSL10's role at ER-plasma membrane contact sites through proteomic and genetic screens in Arabidopsis thaliana.

In vitro experiments and kinetic models of pollen hydration show that MSL8 is not a simple tension-gated osmoregulator

The paper tests if MSL8 functions as a tension-gated osmoregulator in pollen hydration using experiments and models, finding it instead strengthens the cell wall.

The Mechanosensitive Ion Channel MSL10 Modulates Susceptibility to Pseudomonas syringae in Arabidopsis thaliana

This study shows that the mechanosensitive ion channel MSL10 modulates Arabidopsis susceptibility to Pseudomonas syringae by affecting immune responses and stomatal closure.

Regulation of Vacuole Morphology by PIEZO Channels in Spreading Earth Moss

This study investigates the role of PIEZO channels in moss, showing they regulate vacuole morphology and have diverged from animal homologs in function and localization.

Charged Pore-lining Residues are Required for Normal Channel Kinetics in the Eukaryotic Mechanosensitive Ion Channel MSL1

The paper shows that charged pore-lining residues in MSL1 affect channel kinetics and stability, proposing a 'sweet spot' model for mechanosensitive channel function.

Interactions between the N- and C- termini of mechanosensitive ion channel AtMSL10 are consistent with a three-step mechanism for activation

The paper investigates how mutations in the N- and C-termini of the plant mechanosensitive ion channel AtMSL10 trigger cell death and proposes a three-step activation mechanism involving conformational changes and dephosphorylation.

The Mechanosensitive Ion Channel MSL10 Potentiates Responses to Cell Swelling in Arabidopsis Seedlings

This study identifies MSL10 as a phospho-regulated mechanosensitive ion channel that mediates cell swelling responses in Arabidopsis seedlings, including calcium transients, ROS accumulation, and programmed cell death.

Genetic and physical interactions between the organellar mechanosensitive ion channel homologs MSL1, MSL2, and MSL3 reveal a role for inter-organellar communication in plant development

This study shows that MSL1, MSL2, and MSL3 interact genetically and physically, suggesting inter-organellar communication is important for plant development.

Nonpolar Residues in the Presumptive Pore-Lining Helix of Mechanosensitive Channel MSL10 Influence Channel Behavior and Confirm a Non-Conducting Function

This study identifies nonpolar residues in MSL10's pore-lining helix that influence conductance, gating tension, and cell death signaling, showing ion channel function is independent of cell death.