B. White

Structural basis for catalysis and selectivity of phospholipid synthesis by eukaryotic choline-phosphotransferase

The paper presents the structure of yeast CPT1 in multiple substrate-bound states to elucidate the mechanism of phospholipid synthesis and selectivity.

Aalbo1200: global genetic differentiation and variability of the mosquito Aedes albopictus

This study generates whole genome sequencing data from Aedes albopictus populations to analyze genetic differentiation and variability across tropical and temperate regions.

Negative allosteric modulation of the μ-opioid receptor

This paper identifies a negative allosteric modulator of the μ-opioid receptor that blocks agonist activity and enhances naloxone efficacy, offering potential for safer opioid overdose reversal.

Honey contamination from plant protection products approved for cocoa cultivation: a systematic review of existing research and methods

This study reviews 104 publications on honey contamination from pesticides used in cocoa cultivation, finding 169 compounds detected, with neonicotinoids and imidacloprid most prevalent, and noting a lack of research in non-cocoa producing countries.

Oral mTOR Inhibition Limits And Reduces Actinic Keratosis And Cutaneous Squamous Cell Carcinoma In A UVB-Induced Mouse Model

This study shows oral mTOR inhibitors reduce actinic keratosis and cutaneous squamous cell carcinoma in a UVB-induced mouse model by limiting lesion size and frequency.

Prophylactic low-dose, bi-weekly benznidazole treatment fails to prevent Trypanosoma cruzi infection in dogs under intense transmission pressure

This study tests low-dose, bi-weekly benznidazole prophylaxis in dogs under high T. cruzi transmission pressure but finds no reduction in new infections.

Whole genome sequencing of a wild yam species Dioscorea tokoro reveals a genomic region associated with sex

The paper reports the whole genome sequence of Dioscorea tokoro and identifies a genomic region associated with sex determination.

PDXNet Portal: Patient-Derived Xenograft model, data, workflow, and tool discovery

The paper introduces the PDXNet Portal, a centralized resource for PDX models and data, offering analysis workflows and facilitating cancer research collaboration.

Circadian regulation of the transcriptome in a complex polyploid crop

This study investigates circadian regulation of homoeologous gene triads in hexaploid bread wheat, finding imbalanced rhythmic expression and conserved biological processes with Arabidopsis.

Characterization of gut microbiome and metabolome in Helicobacter pylori patients in an underprivileged community in the United States

This study characterizes the gut microbiome and metabolome of H. pylori patients in an underprivileged community, finding altered microbial diversity and fatty acid profiles associated with the infection.

Genome analyses reveal the hybrid origin of the staple food crop white Guinea yam

This study reveals the hybrid origin of white Guinea yam through genomic analysis, showing it arose from crosses between D. praehensilis and D. abyssinica with significant introgression around the SWEETIE gene.

Population-scale prediabetic assessment using HbA1c from menstrual blood

This paper introduces a menstrual blood-based HbA1c test for prediabetes screening, showing it is comparable to venous HbA1c and preferred by users for regular testing.

Inference of tumor cell-specific transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection of cancer

This study infers tumor cell-specific transcription factor binding from cell-free DNA to predict tumor subtypes and detect cancer early.

Machine learning enables detection of early-stage colorectal cancer by whole-genome sequencing of plasma cell-free DNA

This paper uses machine learning on whole-genome sequencing of plasma cell-free DNA to detect early-stage colorectal cancer with high sensitivity and specificity.

Germline Cas9 Expression Yields Highly Efficient Genome Engineering in a Major Worldwide Disease Vector, Aedes aegypti

This paper develops transgenic Cas9 lines in Aedes aegypti for efficient genome editing, enabling high-throughput gene disruption and potential gene drive applications.