Author

E. J. Carr

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:statistical model· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:flow cytometry· 2 Assay:spatial transcriptomics· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

D. L. Hill· 2 shared M. A. Linterman· 2 shared A. E. Denton· 1 shared A. Hobbs· 1 shared A. K. Wheatley· 1 shared A. Liston· 1 shared A. P. Browning· 1 shared A. Riddell· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersImmunology

D. L. Hill

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Author profile →

4 papers

Recent·Most cited

Dichotomy of neutralizing antibody, B cell and T cell responses to SARS-CoV-2 vaccination and protection in healthy adults

E. J. Carr, H. Townsley, M. Y. Wu, K. A. Wilkinson, P. S. Hobson, D. Levi, S. Namjou, H. V. Mears, A. Hobbs, M. Ragno, L. S. Herman, R. Harvey, C. Bailey, A. S. Fowler, E. Hatipoglu, , E. C. Wall

The paper identifies four patterns of SARS-CoV-2 vaccine responses, including broad and narrow responders, and links broad responder traits to longer infection-free time after vaccination.

bioRxiv · May 24, 2023 · PreprintImmunology

A stochastic mathematical model of 4D tumour spheroids with real-time fluorescent cell cycle labelling

J. J. Klowss, A. P. Browning, R. J. Murphy, E. J. Carr, M. J. Plank, G. Gunasingh, N. K. Haass, M. J. Simpson

This paper develops a stochastic individual-based model of 4D tumour spheroids and validates it against experimental data from human melanoma cell line experiments.

bioRxiv · Nov 28, 2021Biophysics

The memory B cell response to influenza vaccination is impaired in older persons

E. J. Carr, A. K. Wheatley, D. L. Hill, M. A. Linterman

This study shows that older adults have impaired memory B cell responses to influenza vaccination, characterized by reduced somatic hypermutation and positive selection in FCRL5+ atypical memory B cells.

bioRxiv · Mar 4, 2021 · PreprintImmunology

Intrinsic defects in lymph node stromal cells underpin poor germinal center responses during aging

A. E. Denton, A. Silva-Cayetano, J. Dooley, D. L. Hill, E. J. Carr, P. A. Robert, M. Meyer-Hermann, A. Liston, M. A. Linterman

This study shows that aging impairs lymph node stromal cells' ability to respond to vaccination, limiting germinal center formation and antibody production.

bioRxiv · May 7, 2020 · PreprintImmunology