V. Ntziachristos

This paper introduces PSOM, a technique for fast live-cell hyperspectral imaging with large FOVs and high confluency, achieving reduced noise and lower photodamage.

This paper introduces a new biosensor, DIROS, for non-invasive blood glucose detection with improved accuracy over existing methods by targeting microvascular glucose in the skin.

This study introduces FP-RSOM to visualize and quantify skin microvascular endothelial dysfunction, showing higher sensitivity than existing methods in detecting cardiovascular risk factors.

This paper introduces Frequency Comb Optoacoustic Tomography (FCOT) and demonstrates its superior signal-to-noise ratio and faster multi-spectral operation compared to traditional time-domain optoacoustics.

This study uses MSOT to non-invasively visualize lipid accumulation in mice with NAFLD, showing its potential for monitoring hepatic steatosis without contrast agents.

This study uses multispectral optoacoustic tomography to non-invasively measure postprandial lipemia in humans, showing significant lipid increases in various tissues after a high-fat meal.

This paper introduces an optoacoustic flow cytometer (OAFC) that uses light scattering as a reference to distinguish E. coli cells based on optoacoustic properties of expressed chromoproteins with over 90% precision.

The paper introduces two photochromic proteins for multiplexed in vivo optoacoustic imaging and develops software to enable temporal signal unmixing in commercial systems.

The paper develops a multimodal laser spectrometer to measure optoacoustic spectra of dyes and proteins, revealing discrepancies between absorption and optoacoustic spectra and uncovering new photophysical properties.

This paper introduces a sparse UNET model for automatic vascular segmentation in MSOT images, achieving high accuracy and reducing manual effort.

This paper introduces a hybrid imaging system to observe zebrafish development beyond the larval stage, enabling long-term studies of adult zebrafish in biomedicine.

This paper introduces a photoacoustic pigment relocalization sensor inspired by cuttlefish chromatophore cells to detect GPCR-mediated signaling molecules in vitro and in vivo.