T. Yuan

The paper introduces the CCLE model to predict chromatin organization in yeast using cohesin ChIP-seq data, showing it accurately predicts TADs without relying on CTCF.

The paper shows that inhibiting mitochondrial DNA transcription in mice increases fatty acid oxidation, reducing obesity and liver fat while decreasing oxidative phosphorylation capacity.

This study shows that titanium dioxide nanoparticles induce fat deposition in mice by increasing ROS and activating the AGE-RAGE pathway, with NAC as a potential therapeutic.

This paper introduces PSOM, a technique for fast live-cell hyperspectral imaging with large FOVs and high confluency, achieving reduced noise and lower photodamage.

This paper establishes the link between microscale fluid-axon interactions and macroscopic brain transport properties using simulations, introducing an anisotropic pressure-dependent permeability tensor.

The paper presents cryo-EM structures of human NaV1.6 channels with and without 4,9-anhydro-tetrodotoxin, revealing Na+ selectivity and inhibition mechanisms.

This paper derives an anisotropic porosity-permeability tensor relationship for brain white matter and proposes a model to improve transport property design in fibrous biomaterials.

This study investigates ovule abortion in Paeonia ludlowii, identifying types, developmental stages, and morphological differences between aborted and fertile ovules.

This study finds that patients with severe SARS-CoV-2 disease have higher antibody titers against viral proteins and neutralization capabilities compared to less severe cases.

This study investigates how loop extrusion factors and chromatin structure influence chromatin dynamics using microscopy, genetics, and simulations in fission yeast.

This study investigates the interaction between S100A4 and S100A1, revealing that S100A4 inhibits cell proliferation by blocking the RAGE V domain-S100A1 interaction.