Kinase Suppressor of RAS 1 (KSR1) maintains the transformed phenotype of BRAFV600E mutant human melanoma cells
Z. Liu, A. Krstic, A. Neve, N. Rauch, K. Wynne, H. Cassidy, A. McCann, E. Kavanagh, B. McCann, A. Blanco, J. Rauch, W. Kolch
This study shows that KSR1 is essential for maintaining the transformed phenotype of BRAFV600E mutant melanoma cells by promoting cell survival and inhibiting senescence and apoptosis.
bioRxiv · Aug 16, 2022Cancer Biology