Author

E. L. Snyder

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. Jones· 2 shared B. T. Spike· 2 shared G. Orstad· 2 shared K. Ingram· 2 shared K. L. Gillis· 2 shared M. C. Mendoza· 2 shared R. Zewdu· 2 shared B. Lohman· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

A. Jones

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Author profile →

3 papers

Recent·Most cited

FoxA1 and FoxA2 regulate growth and cellular identity in NKX2-1-positive lung adenocarcinoma

G. Orstad, G. Fort, T. J. Parnell, A. Jones, C. Stubben, B. Lohman, K. L. Gillis, W. Orellana, R. Tariq, O. Klingbeil, K. H. Kaestner, C. Vakoc, B. T. Spike, E. L. Snyder

This study shows that FoxA1/2 are critical for tumorigenesis and cellular identity in NKX2-1-positive lung adenocarcinoma, with their loss impairing tumor growth and altering transcriptional programs.

bioRxiv · Jun 29, 2021 · PreprintCancer Biology

NKX2-1 controls lung cancer progression by inducing DUSP6 to dampen ERK activity

K. Ingram, S. C. Samson, R. Zewdu, R. G. Zitnay, E. L. Snyder, M. C. Mendoza

This study shows NKX2-1 suppresses lung cancer progression by inducing DUSP6, which reduces ERK activity, and demonstrates this effect in human samples, cell lines, and mouse models.

bioRxiv · Mar 4, 2021Cancer Biology

An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma

R. Zewdu, E. M. Mehrabad, K. Ingram, P. Fang, K. L. Gillis, S. A. Camolotto, G. Orstad, A. Jones, M. C. Mendoza, B. T. Spike, E. L. Snyder

bioRxiv · Feb 25, 2020Cancer Biology