Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
6 papers
Recent·Most cited
J. Xu, J. S. Roe, E. Lee, C. Tonelli, T. Somerville, M. Yao, J. Milazzo, H. Tiriac, A. Kolarzyk, E. Lee, J. Grem, A. Lazenby, J. Grunkemeyer, M. Hollingsworth, A. D. Borowsky, , C.-i. Hwang
This study shows EN1 promotes pancreatic cancer metastasis by repressing target genes and enhancing mesenchymal properties.
bioRxiv · Apr 10, 2023 · PreprintCancer Biology
G. Orstad, G. Fort, T. J. Parnell, A. Jones, C. Stubben, B. Lohman, K. L. Gillis, W. Orellana, R. Tariq, O. Klingbeil, K. H. Kaestner, C. Vakoc, B. T. Spike, E. L. Snyder
This study shows that FoxA1/2 are critical for tumorigenesis and cellular identity in NKX2-1-positive lung adenocarcinoma, with their loss impairing tumor growth and altering transcriptional programs.
bioRxiv · Jun 29, 2021 · PreprintCancer Biology
Y. Wei, S. Iyer, S. Costa, Z. Yang, M. Kramer, E. Adelman, O. Klingbeil, O. Demerdash, S. Polyanskaya, K. Chang, S. Goodwin, E. Hodges, W. R. McCombie, M. Figueroa, C. Vakoc
The paper identifies SLC5A3-dependent myo-inositol auxotrophy in AML through genetic screening and shows synthetic lethality between ISYNA1 and SLC5A3.
bioRxiv · Dec 22, 2020 · PreprintCancer Biology
T. Somerville, Y. Xu, X. Wu, C. Vakoc
This study identifies ZBED2 as a transcriptional repressor that antagonizes IRF1 to modulate cell identity and suppress interferon response in pancreatic cancer.
bioRxiv · Dec 6, 2019Cancer Biology
T. Somerville, G. Biffi, J. Dassler-Plenker, K. Miyabayashi, Y. Xu, D. Maia-Silva, O. Klingbeil, O. Demerdash, M. Egeblad, D. Tuveson, C. Vakoc
This study shows that squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation by converting pancreatic stellate cells into inflammatory CAFs via TP63-dependent mechanisms.
bioRxiv · Nov 6, 2019Cancer Biology
Y. Tarumoto, S. Lin, J. Wang, J. Milazzo, Y. Xu, N. Gray, K. Stegmaier, C. Vakoc
This study shows that the SIK3 inhibitor YKL-05-099 suppresses MEF2C function and slows AML progression in mouse models.
bioRxiv · May 14, 2019 · PreprintCancer Biology