Timing of treatment shapes the path to androgen receptor signaling inhibitor resistance in prostate cancer
E. Lee, Z. Zhang, C.-C. Chen, D. Choi, A. C. A. Rivera, E. Linton, Y.-j. Ho, J. Love, J. LaClair, J. Wongvipat, C. Sawyers
This study shows that treatment timing affects the path to androgen receptor signaling inhibitor resistance in prostate cancer, with resistance arising through different mechanisms depending on the tumor context.
bioRxiv · Mar 18, 2024 · PreprintCancer Biology