ImmunologybioRxivPreprint
The pore-forming protein gasdermin D is a cellular redox sensor
P. Devant, E. Borsic, E. M. Ngwa…·J. C. Kagan
This study shows that reactive oxygen species (ROS) oxidize gasdermin D (GSDMD), promoting its assembly into a pore-forming complex and enhancing pyroptosis.
DOI 10.1101/2022.03.11.484021