Alpha cell dysfunction in early type 1 diabetes
N. Doliba, A. Rozo, J. Roman, W. Qin, D. Traum, L. Gao, J. Liu, E. Manduchi, C. Liu, M. Golson, G. Vahedi, A. Naji, F. Matschinsky, M. Atkinson, A. Powers, , D. Stoffers
The paper identifies early alpha cell dysfunction in individuals with GADA+ status, preceding beta cell loss in T1D, and links it to metabolic pathway abnormalities.
bioRxiv · Oct 15, 2021 · PreprintPhysiology