G. Lopez

Tumor infiltrating iNKT cells sustain neutrophil pro-tumorigenic functions influencing disease progression in human colorectal cancer

The paper shows tumor-infiltrating iNKT cells have pro-tumorigenic effects in CRC by promoting neutrophil functions and poor patient outcomes.

Arabidopsis Leucine Rich Repeat-Malectin Receptor Kinases in immunity triggered by cellulose and mixed-linked glucan oligosaccharides

This study identifies three Arabidopsis RLKs with LRR and MAL domains that recognize cellulose and MLG-derived oligosaccharides, triggering PTI, distinct from chitin recognition.

ALT in Pediatric High-Grade Gliomas Can Occur without ATRX Mutation and is Enriched in Patients with Pathogenic Germline MMR Variants

This paper identifies ALT in pediatric high-grade gliomas without ATRX mutations and links it to germline MMR variants.

PD-L1ATTAC mice reveal the potential of targeting PD-L1 expressing cells in cancer therapy

The paper develops PD-L1ATTAC mice to study PD-L1-expressing cells' role in cancer and immunity, finding their elimination enhances antitumor immunity and worsens septic responses.

Integrative genomics identifies lncRNA regulatory networks across 1,044 pediatric leukemias and extra-cranial solid tumors

The paper identifies lncRNA regulatory networks in pediatric cancers using integrated genomics data from 1,044 samples, revealing their roles in proliferation, metabolism, and DNA damage.

Neutrophil extracellular traps induce the epithelial-mesenchymal transition: implications in post-COVID-19 fibrosis

This study shows that neutrophil extracellular traps (NETs) induce epithelial-mesenchymal transition (EMT) in lung cells, contributing to post-COVID-19 fibrosis.

Cell-to-cell Mathematical Modeling of Arrhythmia Phenomena in the Heart

This study simulates arrhythmia phenomena in cardiac tissue using two cell topologies and identifies initial conditions that lead to fibrillation evolving into fluttering.

Arabidopsis cell wall composition determines disease resistance specificity and fitness

This study shows that Arabidopsis cell wall composition affects disease resistance to different pathogens and trade-offs in plant fitness.

Cell-to-cell Mathematical modeling of arrhythmia phenomena in excitable media

The paper models arrhythmias using cellular automaton and ordinary differential equations to simulate fibrillation, fluttering, and their sequences in a two-dimensional cell network.