Ageing impairs the neuro-vascular interface in the heart
J. Wagner, L. Tombor, P. Malacarne, L.-M. Kettenhausen, J. Panthel, M. Cipca, K. Stilz, A. Fischer, M. Muhly-Reinholz, W. Abplanalp, D. John, G. Buchmann, S. Angerdohr, E. Amir, K. Scherschel, , S. Dimmeler
This study shows aging reduces nerve density in the left ventricle and dysregulates neuro-regulatory genes, leading to reduced heart rate variability.
bioRxiv · Jul 29, 2022 · PreprintPhysiology