Pharmacology & ToxicologybioRxivPreprint
Functional modulation of PTH1R activation and signalling by RAMP2
K. Nemec, H. Schihada, G. Kleinau…·I. Maiellaro
This study shows RAMP2 modulates PTH1R activation and signalling, enhancing Gi3 sensitivity and β-arrestin2 recruitment in a ligand-dependent manner.
DOI 10.1101/2021.12.08.471790