P. Scheerer

MRAP2 modifies signaling and oligomerization state of the melanocortin-4 receptor

This study shows that MRAP2 modifies MC4R signaling and oligomerization, enhancing G protein signaling while reducing beta-arrestin2 recruitment and receptor internalization.

T cell interaction partners of DHHC20

This study identifies DHHC20 interaction partners in T cells, showing it interacts with Gsβ1γ2 and suggests a model for its role in palmitoylation.

Is the neuropeptide PEN a ligand of GPR83?

This study investigates whether PEN is a ligand of GPR83 and finds no evidence supporting this claim through multiple assays.

Time-resolved cryo-EM reveals early ribosome assembly in action

The paper uses time-resolved cryo-EM to study early ribosome assembly in bacteria, revealing domain-wise and incremental assembly mechanisms and cooperative rRNA folding.

Functional modulation of PTH1R activation and signalling by RAMP2

This study shows RAMP2 modulates PTH1R activation and signalling, enhancing Gi3 sensitivity and β-arrestin2 recruitment in a ligand-dependent manner.

Structures of active melanocortin-4 receptor--Gs-protein complexes with NDP-α-MSH and setmelanotide

The paper presents cryo-EM structures of MC4R-Gs complexes with NDP-α-MSH and setmelanotide, revealing ligand-specific interactions and activation mechanisms.

Phytochrome mediated responses in Agrobacterium fabrum: growth, swimming, plant infection and interbacterial competition

This study investigates how phytochromes in Agrobacterium fabrum affect DNA transfer, growth, swimming, and interbacterial competition, distinguishing light-regulated and light-independent responses.