Author

E. P. Geissler

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Biology Disciplines

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Biochemistry· 1

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. D'Oliviera· 1 shared J. S. Mugridge· 1 shared L. Etienne· 1 shared S. Mottaghinia· 1 shared S. Olson· 1 shared X. Dai· 1 shared Y. Zhang· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. D'Oliviera

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1 paper

Recent·Most cited

BiochemistrybioRxivFeb 20, 2023

Recognition and Cleavage of Human tRNA Methyltransferase TRMT1 by the SARS-CoV-2 Main Protease

A. D'Oliviera, X. Dai, S. Mottaghinia…·J. S. Mugridge

This study identifies TRMT1 as a target of SARS-CoV-2 Mpro, showing cleavage disrupts its tRNA methyltransferase activity and impacts host translation and oxidative stress response.

DOI 10.7554/elife.91168.3

humanproteomics

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