Pharmacology & ToxicologybioRxiv
Chemogenetic analysis of how receptors for short chain fatty acids regulate the gut-brain axis
A. B. Tobin, N. Barki, D. Bolognini…·G. Milligan
This study identifies a specific agonist for a modified FFA2 receptor and demonstrates distinct roles of FFA2 and FFA3 in gut-brain communication using genetically engineered mice.
DOI 10.7554/elife.73777