The two zinc fingers in the nucleocapsid domain of the HIV-1 Gag precursor are equivalent for the interaction with the genomic RNA in the cytoplasm, but not for the recruitment of the complexes at the plasma membrane
S. Bernacchi, E. Boutant, J. Bonzi, H. Anton, M. B. Nasim, R. Cathagne, E. Real, D. Dujardin, P. Carl, P. Didier, J.-C. Paillart, R. Marquet, Y. Mely, H. de Rocquigny
This study investigates the role of zinc fingers in HIV-1 Gag's interaction with genomic RNA and their contribution to complex recruitment at the plasma membrane.
Biophysical Journal · Jul 1, 2020Peer-reviewedBiophysics