A. Reyes-Sandoval

This study shows that poor immunogenicity of EEF antigens does not prevent their susceptibility to CD8+ T cell killing, challenging the assumption that immunogenicity is a key criterion for vaccine development.

A four-step process isolates pure malaria sporozoites from mosquitoes without manual dissection, enabling a whole-parasite vaccine that provides sterilizing protection.

This study shows that the SYIPSAEKI epitope of Plasmodium berghei CSP is critical for CD8+ T cell-mediated protection against malaria, but not essential for vaccine-induced immunity in all mouse strains.

This study shows that drug-cured Trypanosoma cruzi infections in mice provide long-lasting, cross-strain immunity against re-infection, outperforming recombinant vaccines.

This paper evaluates a ZIKV vaccine based on chimpanzee adenovirus ChAdOx1, showing it provides sterile immunity against both Asian and African lineages and prevents viral colonization of brain and ovaries.