Author

E. S. Matthees

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Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Godbole· 1 shared C. Hoffmann· 1 shared J. C. Filor· 1 shared J. Drube· 1 shared M. Reichel· 1 shared N. Jaiswal· 1 shared N. Youssef· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Godbole

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1 paper

Recent·Most cited

Pharmacology & ToxicologybioRxivJul 14, 2023

GRK specificity and beta gamma dependency determines a GPCR`s potential in biased agonism

E. S. Matthees, J. C. Filor, N. Jaiswal…·C. Hoffmann

This paper shows that GRK2/3's interaction with Gβγ is essential for β-arrestin2 recruitment to GPCRs, linking G protein activation to biased agonism potential.

DOI 10.1038/s42003-024-06490-1

experimental assayhost-pathogen & immune response

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