Steroid hormone imbalance drives macrophage infiltration and Spp1/osteopontin+ foam cell differentiation in the prostate
P. Popovics, K. O. Skalitzky, E. Schroeder, A. Jain, S. V. Silver, F. Van Fritz, K. S. Uchtmann, C. M. Vezina, W. A. Ricke
This study shows that steroid hormone imbalance in mice increases macrophage infiltration and Spp1/osteopontin+ foam cell differentiation in the prostate, with OPN knockout reducing these effects.
bioRxiv · Dec 13, 2022Pathology