CDK8 and CDK19 act redundantly to control the CFTR pathway in the intestinal epithelium
S. Prieto, G. Dubra, A. Camasses, E. Simboeck, A. B. Aznar, C. Begon-Pescia, N. Pirot, F. Gerbe, L. Angevin, P. Jay, L. Krasinska, D. Fisher
The paper shows CDK8 and CDK19 redundantly regulate the CFTR pathway in intestinal epithelium, leading to mucus accumulation and goblet cell secretion when both are deleted.
bioRxiv · Jan 28, 2022Cell Biology