Author

G. Dubra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Research Focus:differential expression· 1

Frequent Co-Authors

D. Fisher· 4 shared L. Krasinska· 3 shared S. Prieto· 3 shared A. B. Aznar· 2 shared A. Camasses· 2 shared N. Pirot· 2 shared A. J. R. Heck· 1 shared A. Lozano· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersCell Biology

D. Fisher

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

CDK8 and CDK19 act redundantly to control the CFTR pathway in the intestinal epithelium

S. Prieto, G. Dubra, A. Camasses, E. Simboeck, A. B. Aznar, C. Begon-Pescia, N. Pirot, F. Gerbe, L. Angevin, P. Jay, L. Krasinska, D. Fisher

The paper shows CDK8 and CDK19 redundantly regulate the CFTR pathway in intestinal epithelium, leading to mucus accumulation and goblet cell secretion when both are deleted.

bioRxiv · Jan 28, 2022Cell Biology

Single-embryo phosphoproteomics reveals the importance of intrinsic disorder in cell cycle dynamics

J. M. Valverde, G. Dubra, H. van den Toorn, G. van Mierlo, M. Vermeulen, A. J. R. Heck, P. Knipscheer, L. Krasinska, D. Fisher, M. Altelaar

The paper uses single-embryo phosphoproteomics to show that phosphorylation of intrinsically disordered proteins by cell cycle kinases drives switch-like mitotic reorganization.

bioRxiv · Aug 29, 2021 · PreprintCell Biology

Ki-67 promotes sequential stages of tumourigenesis by enabling cellular plasticity

K. Mrouj, P. Singh, M. Sobecki, G. Dubra, E. Al Ghoul, A. B. Aznar, S. prieto, N. Pirot, F. Bernex, B. Bordignon, C. Hassen-Khodja, M. Pouzolles, V. Zimmerman, V. Dardalhon, L. Krasinska, D. Fisher

This study shows Ki-67 enables cellular plasticity across tumourigenesis stages, with knockout inhibiting tumour growth and metastasis through transcriptome remodelling and angiogenesis disruption.

bioRxiv · Dec 13, 2019Cancer Biology

CDK8 and CDK19 kinases have non-redundant oncogenic functions in hepatocellular carcinoma

K. Bacevic, S. Prieto, S. Caruso, A. Camasses, G. Dubra, J. Ursic-Bedoya, A. Lozano, J. Butterworth, J. Zucman-rossi, U. Hibner, D. Fisher, D. Gregoire

The paper investigates the roles of CDK8 and CDK19 in hepatocellular carcinoma, finding they are overexpressed and have non-redundant oncogenic functions that interact with TP53.

bioRxiv · Oct 1, 2019 · PreprintCancer Biology