Author

E. Touizer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Assay:proteomics· 3 Assay:flow cytometry· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

L. E. McCoy· 3 shared L. Muir· 3 shared C. Rees-Spear· 2 shared C. Roustan· 2 shared D. Peppa· 2 shared E. Gea-Mallorqui· 2 shared F. Burns· 2 shared J. Kopycinski· 2 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

L. E. McCoy

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Preservation of memory B cell homeostasis in an individual producing broadly neutralising antibodies against HIV-1

S. Griffith, L. Muir, O. Suchanek, J. Hope, C. Pade, J. M. Gibbons, Z. K. Tuong, A. Fung, E. Touizer, C. Rees-Spear, A. Nans, C. Roustan, Y. Alguel, D. Fink, C. Orkin, , L. E. McCoy

The paper isolates a broadly neutralizing HIV-1 antibody from an untreated HIV-1 patient and shows memory B cells remain functional despite viral infection.

bioRxiv · Feb 5, 2024 · PreprintMicrobiology

Attenuated humoral responses in HIV infection after SARS-CoV-2 vaccination are linked to global B cell defects and cellular immune profiles

E. Touizer, A. Alrubbayi, R. Ford, N. Hussain, P. Pereyra Gerber, H.-L. Shum, C. Rees-Spear, L. Muir, E. Gea-Mallorqui, J. Kopycinski, D. Jankovic, C. Pinder, T. A. Fox, I. Williams, C. Mullender, , L. E. McCoy

This study examines humoral and cellular immune responses to SARS-CoV-2 vaccination in HIV-infected individuals, finding reduced antibody responses and B cell dysfunction, but robust T cell responses.

bioRxiv · Nov 11, 2022 · PreprintImmunology

Characterization of humoral and SARS-CoV-2 specific T cell responses in people living with HIV

A. Alrubayyi, E. Gea-Mallorqui, E. Touizer, D. Hameiri-Bowen, J. Kopycinski, B. Charlton, N. Fisher-Pearson, L. Muir, A. Rosa, C. Roustan, C. Earl, P. Cherepanov, P. Pellegrino, L. Waters, F. Burns, , D. Peppa

This study examines SARS-CoV-2-specific immune responses in people living with HIV on ART, finding comparable antibody and T cell responses to HIV-negative individuals, with T cell magnitude linked to CD4 T cell pool size and CD4:CD8 ratio.

bioRxiv · Feb 15, 2021Immunology

Disrupting HIV-1 capsid formation causes cGAS sensing of viral DNA

R. P. Sumner, L. Harrison, E. Touizer, T. P. Peacock, M. Spencer, L. Zuliani-Alvarez, G. J. Towers

The paper shows that disrupting HIV-1 capsid formation exposes viral DNA to cGAS, triggering an IFN response in macrophages.

bioRxiv · Nov 11, 2019Microbiology