CTCF orchestrates long-range cohesin-driven V(D)J recombinational scanning
Z. Ba, J. Lou, E. W. Dring, A. Y. Ye, S. G. Lin, S. Jain, K.-R. Kieffer-Kwon, R. Casellas, F. W. Alt
This study shows that CTCF degradation promotes distal VH-to-DJH joining by enabling cohesin-driven RAG-scanning in pro-B cells.
bioRxiv · Jan 1, 2020Immunology