Author

Z. Ba

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:chromatin & epigenetic regulation· 3 Assay:DNA methylation· 3 Assay:ChIP-seq· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Y. Ye· 3 shared F. W. Alt· 3 shared H.-Q. Dai· 2 shared J. Lou· 2 shared R. Casellas· 2 shared S. G. Lin· 2 shared Y. Zhang· 2 shared A. Conte· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersImmunology

A. Y. Ye

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4 papers

Recent·Most cited

Core enhancers of the 3'RR optimize IgH nuclear position and loop conformation for oriented CSR

C. Bruzeau, J. Pollet, M. Thomas, Z. Ba, D. Roulois, E. PINAUD, S. Le Noir

The paper shows that core enhancers of the IgH 3RR preorganize B cell nuclei to facilitate class switch recombination by controlling nuclear positioning and loop formation.

bioRxiv · Jul 11, 2023 · PreprintImmunology

Contribution of the IGCR1 regulatory element and the 3'Igh CBEs to Regulation of Igh V(D)J Recombination

Z. Liang, L. Zhao, A. Y. Ye, S. G. Lin, Y. Zhang, C. Guo, H.-Q. Dai, Z. Ba, F. W. Alt

This study investigates how IGCR1 regulatory elements and 3'Igh CBEs influence RAG-scanning and V(D)J recombination in progenitor-B cells through chromatin loop extrusion and WAPL down-regulation.

bioRxiv · Apr 21, 2023 · PreprintImmunology

Loop Extrusion Mediates Physiological Locus Contraction for V(D)J Recombination

H.-Q. Dai, H. Hu, J. Lou, A. Y. Ye, A. M. Chapdelaine-Williams, N. Kyritsis, Y. Zhang, N. Manfredonia, R. Judson, H. Chen, K. Johnson, S. Lin, Z. Ba, A. Conte, R. Casellas, , F. W. Alt

The paper shows that locus contraction and V(D)J recombination are regulated by circumventing CBE scanning impediments through Wapl-dependent cohesin dynamics.

bioRxiv · Jun 30, 2020 · PreprintImmunology

CTCF orchestrates long-range cohesin-driven V(D)J recombinational scanning

Z. Ba, J. Lou, E. W. Dring, A. Y. Ye, S. G. Lin, S. Jain, K.-R. Kieffer-Kwon, R. Casellas, F. W. Alt

This study shows that CTCF degradation promotes distal VH-to-DJH joining by enabling cohesin-driven RAG-scanning in pro-B cells.

bioRxiv · Jan 1, 2020Immunology