ImmunologybioRxiv
CTCF orchestrates long-range cohesin-driven V(D)J recombinational scanning
Z. Ba, J. Lou, E. W. Dring…·F. W. Alt
This study shows that CTCF degradation promotes distal VH-to-DJH joining by enabling cohesin-driven RAG-scanning in pro-B cells.
DOI 10.1038/s41586-020-2578-0