ImmunologybioRxiv
Accurate Immune Repertoire Sequencing Reveals Malaria Infection Driven Antibody Lineage Diversification in Young Children
B. S. Wendel, C. He, M. Qu…·N. Jiang
The paper introduces a high-coverage antibody repertoire sequencing method, MIDCIRS, and uses it to show increased somatic hypermutation in infants and toddlers during malaria infection.