ImmunologybioRxiv
Activation of a Latent Epitope Causing Differential Binding of Anti-Neutrophil Cytoplasmic Antibodies to Proteinase 3
M. Casal Moura, G. E. Thompson, D. A. Nelson…·U. Specks
The paper investigates how mutations in PR3 affect PR3-ANCA binding, finding increased binding to a variant with specific mutations.
DOI 10.1002/art.42418