Author

D. Emerling

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:protein structure· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Organism:plant (other)· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

W. Volkmuth· 3 shared A. M. Hummel· 2 shared C. R. King· 2 shared D. E. Jenne· 2 shared D. Oyen· 2 shared E. Locke· 2 shared F. Zavala· 2 shared G. E. Thompson· 2 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersImmunology

W. Volkmuth

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Activation of a Latent Epitope Causing Differential Binding of Anti-Neutrophil Cytoplasmic Antibodies to Proteinase 3

M. Casal Moura, G. E. Thompson, D. A. Nelson, L. A. Fussner, A. M. Hummel, D. E. Jenne, D. Emerling, W. Volkmuth, F. C. Fervenza, C. G. M. Kallenberg, C. A. Langford, J. W. McCune, P. A. Merkel, P. A. Monach, P. Seo, , U. Specks

The paper investigates how mutations in PR3 affect PR3-ANCA binding, finding increased binding to a variant with specific mutations.

bioRxiv · Oct 25, 2022Immunology

Affinity-matured homotypic interactions induce spectrum of PfCSP-antibody structures that influence protection from malaria infection

G. Martin, J. L. Torres, T. Pholcharee, D. Oyen, Y. Flores-Garcia, G. Gibson, R. Moskovitz, N. Beutler, D. D. Jung, J. Copps, W.-H. Lee, G. Gonzalez-Paez, D. Emerling, R. S. MacGill, E. Locke, , A. Ward

The paper analyzes structural and functional properties of antibodies targeting PfCSP, showing how homotypic interactions and affinity maturation influence protection against malaria.

bioRxiv · Sep 20, 2022Immunology

Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum

T. Pholcharee, D. Oyen, Y. Flores-Garcia, G. Gonzalez-Paez, Z. Han, K. L. Williams, W. Volkmuth, D. Emerling, E. Locke, C. R. King, F. Zavala, I. A. Wilson

The paper analyzes eight anti-NANP antibodies from a malaria vaccine trial, linking their structural and biophysical properties to in vivo protection against P. falciparum.

bioRxiv · Jul 18, 2020Microbiology

Remote Activation of a Latent Epitope in an Autoantigen Decoded with Simulated B-Factors

Y.-P. Pang, M. Casal Moura, G. E. Thompson, D. R. Nelson, A. M. Hummel, D. E. Jenne, D. Emerling, W. Volkmuth, W. H. Robinson, U. Specks

The paper shows that remote mutations in PR3 can activate a latent epitope, enabling antibody binding, and suggests using B-factor analysis to design therapeutics targeting autoantigens.

bioRxiv · Aug 10, 2019Biophysics