Author

E. Webb

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

A. Oztekin· 2 shared X. Cheng· 2 shared X. F. Zhang· 2 shared A. Serrels· 1 shared C. Dong· 1 shared E. Bullock· 1 shared G. Dodd· 1 shared M. C. Frame· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiophysics

A. Oztekin

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Loss of the adhesion protein Kindlin-1 stimulates tumor clearance via modulation of Tregs

E. Webb, G. Dodd, E. Bullock, M. Muir, M. C. Frame, A. Serrels, V. Brunton

This study shows that loss of Kindlin-1 in breast cancer cells reduces tumor growth by decreasing Treg numbers and function, mediated by increased IL-6 secretion.

bioRxiv · Mar 4, 2022Cancer Biology

Long time-scale study of von Willebrand factor multimers in extensional flow

E. Webb, S. Kania, A. Oztekin, X. Cheng, X. F. Zhang

This study uses WEBD simulations to analyze vWF multimer unfolding in extensional flow, showing that pathological unfolding is unlikely below 2000 s-1 strain rate.

bioRxiv · Sep 9, 2020 · PreprintBiophysics

Internal Tensile Force and A2 Domain Unfolding of von Willebrand Factor Multimers in Shear Flow

M. J. Morabito, C. Dong, W. Wei, X. F. Zhang, X. Cheng, A. Oztekin, E. Webb

This study uses simulations to show that A2 domain unfolding in vWF multimers under shear flow occurs preferentially near the center of unraveled multimers, with threshold shear rates inversely related to multimer length.

bioRxiv · May 2, 2018Biophysics