Author

A. Serrels

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

M. Muir· 2 shared B. R. Walker· 1 shared C. T. Davidson· 1 shared E. Bullock· 1 shared E. Miller· 1 shared E. Webb· 1 shared G. Dodd· 1 shared J. C. Dawson· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

M. Muir

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Loss of the adhesion protein Kindlin-1 stimulates tumor clearance via modulation of Tregs

E. Webb, G. Dodd, E. Bullock, M. Muir, M. C. Frame, A. Serrels, V. Brunton

This study shows that loss of Kindlin-1 in breast cancer cells reduces tumor growth by decreasing Treg numbers and function, mediated by increased IL-6 secretion.

bioRxiv · Mar 4, 2022Cancer Biology

11β-HSD1 inhibition does not affect murine tumour angiogenesis but may exert a selective effect on tumour growth by modulating inflammation and fibrosis

C. T. Davidson, E. Miller, M. Muir, J. C. Dawson, M. Lee, S. Aitken, A. Serrels, S. P. Webster, N. Z. M. Homer, R. Andrew, V. G. Brunton, P. W. F. Hadoke, B. R. Walker

This study investigates the effect of 11β-HSD1 inhibition on tumour growth and angiogenesis in murine models, finding increased SCC tumour growth but no effect on angiogenesis.

bioRxiv · Aug 4, 2021 · PreprintCancer Biology