Author

E. Y. Lemma

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Letian· 1 shared N. Dephoure· 1 shared N. K. Altorki· 1 shared P. Cavaliere· 1 shared T. E. McGraw· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

A. Letian

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintSep 17, 2021

Proximity proteome mapping reveals PD-L1-dependent pathways disrupted by anti-PD-L1 antibody specifically in EGFR-mutant lung cancer cells.

A. Letian, E. Y. Lemma, P. Cavaliere…·T. E. McGraw

The paper uses proximity proteome mapping to show that anti-PD-L1 therapy disrupts specific PD-L1-dependent pathways in EGFR-mutant lung cancer cells, leading to altered cell migration and EGFR stability.

DOI 10.1101/2021.09.17.460833

humanproteomics

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