Author

Eileen M. Bates

Michael G. DeGroote Institute for Infectious Disease Research

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Microbiology· 1

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Organism:bacteria (other)· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1

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Alexander BelyyiD· 1 shared Dmitry ShatskiyiD· 1 shared Jake ColauttiiD· 1 shared John C. C. WhitneyiD· 1 shared Nathan P. BulleniD· 1 shared

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Alexander BelyyORCID

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1 paper

Recent·Most cited

MicrobiologyCell ReportsPeer-reviewedSep 1, 2025

Cryo-EM structure of a type VI secretion system delivered membrane-depolarizing toxin involved in bacterial antagonism

Jake Colautti, Dmitry Shatskiy, Eileen M. Bates…·John C. C. Whitney

The paper presents the cryo-EM structure of Ptx2, a VasX family effector, revealing its multi-domain architecture and conformational flexibility, and identifies key features for its toxic activity.

7 citations

bacteria (other)cryo-EM

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