Author

Nathan P. Bullen

Michael G. DeGroote Institute for Infectious Disease ResearchORCID 0000-0003-2552-7944Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Assay:cryo-EM· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

John C. C. WhitneyiD· 2 shared Alexander BelyyiD· 1 shared Breck A. DuerkopiD· 1 shared Cydney N. JohnsoniD· 1 shared Dmitry ShatskiyiD· 1 shared Eileen M. Bates· 1 shared Garima Arya· 1 shared Jake ColauttiiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

John C. C. WhitneyORCID

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2 papers

Recent·Most cited

MicrobiologyCell ReportsPeer-reviewedSep 1, 2025

Cryo-EM structure of a type VI secretion system delivered membrane-depolarizing toxin involved in bacterial antagonism

Jake Colautti, Dmitry Shatskiy, Eileen M. Bates…·John C. C. Whitney

The paper presents the cryo-EM structure of Ptx2, a VasX family effector, revealing its multi-domain architecture and conformational flexibility, and identifies key features for its toxic activity.

7 citations

bacteria (other)cryo-EM

𝕏 PostBluesky

MicrobiologyNature CommunicationsPeer-reviewedAug 13, 2024

An enterococcal phage protein broadly inhibits type IV restriction enzymes involved in antiphage defense

Nathan P. Bullen, Cydney N. Johnson, Shelby E. Andersen…·Breck A. Duerkop

The paper identifies a phage protein that inhibits type IV restriction enzymes in drug-resistant enterococci, revealing how phages evolve to overcome bacterial defense mechanisms.

16 citations

bacteria (other)experimental assay

𝕏 PostBluesky