Emil Kriukov

The paper constructs a lifespan single-cell atlas of the human developing hippocampus and benchmarks iPSC-derived brain organoids with a PSEN1 mutation linked to familial Alzheimer's disease.

This study improves human donor retinal ganglion cell survival by modulating host microglia using annexin V and soluble Fas ligand, increasing survival by 2.5-fold.

The paper introduces scCS, a framework for quantifying cell fate commitment parameters in single-cell transcriptomics, using methods like DFFP and providing diagnostics and visualizations.

This paper shows that adrenergic signaling coordinates systemic and local stem cell activation after amputation in axolotls, enhancing regeneration.

The paper shows that sustained neurotrophic factor cotreatment improves survival of donor and host retinal ganglion cells in a mouse model of optic neuropathy.

The paper constructs a scRNA-seq atlas of human fetal retina to map retinal ganglion cell maturation trajectories and identify intrinsic and extrinsic factors across developmental stages.

The paper constructs a single-cell atlas of human retinal organoids to study development and identify novel transcriptional states.

This study uses single-cell RNA sequencing to analyze retinal myeloid cell activation following human neuron transplantation, revealing reversible activation trajectories similar to disease-associated microglia.

This study identifies DNMT3a as a key inhibitor of optic nerve regeneration in adult mice and shows that its suppression restores vision after injury.