Molecular BiologyPLOS PathogensPeer-reviewed
A conserved interaction between a C-terminal motif in Norovirus VPg and the HEAT-1 domain of eIF4G is essential for translation initiation
Eoin N Leen, Frédéric Sorgeloos, Samantha Correia…·Stephen Curry
This study identifies a conserved C-terminal motif in norovirus VPg that binds to eIF4G HEAT-1 domain, essential for translation initiation and a potential antiviral target.
DOI 10.1371/journal.ppat.1005379