Cell BiologyArteriosclerosis Thrombosis and Vascular BiologyPeer-reviewed
Collagen receptor GPVI-mediated platelet activation and pro-coagulant activity aggravates inflammation and aortic wall remodelling in abdominal aortic aneurysm
Tobias Feige, Agnes Bosbach, Kim Jürgen Krott…·Margitta Elvers
This study shows that GPVI-mediated platelet activation worsens AAA by promoting inflammation and aortic wall remodeling, suggesting GPVI as a therapeutic target.