Author

F. Baas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Pitiriciu· 1 shared C. Schmidt· 1 shared D. de Jong· 1 shared E. B. van den Akker· 1 shared E. P. Ramsay· 1 shared F. J. Staal· 1 shared H. Holstege· 1 shared J. Martinez· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. Pitiriciu

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Author profile →

2 papers

Recent·Most cited

Assembly defects of the human tRNA splicing endonuclease contribute to impaired pre-tRNA processing in pontocerebellar hypoplasia

S. Sekulovski, P. Devant, S. Panizza, T. Gogakos, A. Pitiriciu, K. Heitmeier, E. P. Ramsay, M. Barth, C. Schmidt, S. Weitzer, T. Tuschl, F. Baas, J. Martinez, S. Trowitzsch

This study shows that TSEN assembly defects in PCH patients impair pre-tRNA processing by reducing cleavage activity despite normal endonuclease activity.

bioRxiv · Aug 3, 2020Biochemistry

DYNAMIC CLONAL HEMATOPOIESIS AND FUNCTIONAL T-CELL IMMUNITY IN A SUPER-CENTENARIAN

E. B. van den Akker, S. Makrodimitris, M. Hulsman, M. H. Brugman, T. Nikolic, T. Bradley, Q. Waisfisz, F. Baas, M. E. Jakobs, D. de Jong, P. E. Slagboom, F. J. Staal, M. J. Reinders, H. Holstege

This study examines clonal hematopoiesis and T-cell immunity in a supercentenarian, finding dynamic clonal expansion and preserved T-cell function despite extreme age.

bioRxiv · Jun 4, 2020Immunology