Author

S. Weitzer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:structural biology· 2 Approach:biophysical modeling· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

J. Martinez· 2 shared A. Chui· 1 shared A. Kroupova· 1 shared A. Leitner· 1 shared A. Pitiriciu· 1 shared C. Schmidt· 1 shared E. P. Ramsay· 1 shared F. Ackle· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

J. Martinez

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2 papers

Recent·Most cited

Molecular architecture of the human tRNA ligase complex

A. Kroupova, F. Ackle, F. M. Boneberg, A. Chui, S. Weitzer, M. Faini, A. Leitner, R. Aebersold, J. Martinez, M. Jinek

This study presents biochemical and structural analysis of the human tRNA ligase complex, revealing its molecular architecture and catalytic mechanism.

bioRxiv · Jul 11, 2021Biochemistry

Assembly defects of the human tRNA splicing endonuclease contribute to impaired pre-tRNA processing in pontocerebellar hypoplasia

S. Sekulovski, P. Devant, S. Panizza, T. Gogakos, A. Pitiriciu, K. Heitmeier, E. P. Ramsay, M. Barth, C. Schmidt, S. Weitzer, T. Tuschl, F. Baas, J. Martinez, S. Trowitzsch

This study shows that TSEN assembly defects in PCH patients impair pre-tRNA processing by reducing cleavage activity despite normal endonuclease activity.

bioRxiv · Aug 3, 2020Biochemistry