F. Begum

HEATR5B associates with dynein-dynactin and selectively promotes motility of AP1-bound endosomal membranes

This study identifies HEATR5B as a novel dynein-dynactin interactor that promotes AP1-bound endosomal membrane motility and Golgi transport in human and Drosophila cells.

Detection of Ramularia collo-cygni from barley (Hordeum vulgare) in Australia using triplex quantitative and digital PCR

This study develops a triplex PCR assay for specific detection of Ramularia collo-cygni in barley, confirming its presence across southern Australian barley-growing regions.

GOLPH3 and GOLPH3L are broad-spectrum COPI adaptors for sorting into intra-Golgi transport vesicles

This study identifies GOLPH3 and GOLPH3L as broad-spectrum COPI adaptors that interact with diverse Golgi enzymes to regulate glycosylation pathways.

Interactome analysis of C. elegans synapses by TurboID-based proximity labeling

The paper optimizes a TurboID proximity labeling protocol for C. elegans to characterize tissue and synaptic proteomes, identifying both known and novel proteins.

Two mutations P/L and Y/C in SARS-CoV-2 helicase domain exist together and influence helicase RNA binding

The paper identifies two mutations in SARS-CoV-2 helicase, P504L and Y541C, which have opposing effects on RNA binding affinity and are co-existing in some isolates.

Tumor microtubes connect pancreatic cancer cells in an Arp2/3 complex-dependent manner

This study identifies tumor microtubes (TMTs) in pancreatic cancer cells, showing they depend on the Arp2/3 complex for assembly and differ structurally from tunneling nanotubes.

In vivo identification of GTPase interactors by mitochondrial relocalization and proximity biotinylation

The paper introduces MitoID, a method to identify GTPase effectors and regulators using mitochondrial relocalization and proximity biotinylation, validating novel interactors for Rab, Rho, and Ras family GTPases.