S. L. Bullock

This study identifies a mutation in dynein that causes mitotic spindle arrest independent of the spindle assembly checkpoint, revealing a load-dependent role in anaphase progression.

This study identifies HEATR5B as a novel dynein-dynactin interactor that promotes AP1-bound endosomal membrane motility and Golgi transport in human and Drosophila cells.

The paper uses a CRISPR screen to identify genes critical for dynein-based trafficking, revealing novel regulators and functional relationships in microtubule transport.

This study shows Tm1-I/C coordinates kinesin-1 and dynein during oskar mRNA transport by inhibiting kinesin-1 until it is needed in the oocyte.

The paper shows that Staufen and Egl interact to switch motor proteins during oskar mRNA transport in Drosophila oocytes, enabling proper localization.

This study shows Lis1 activates dynein motility by releasing it from auto-inhibition and promoting complex formation with dynactin, enhancing transport efficiency.

The paper reconstitutes microtubule minus end-directed mRNA transport using purified components and shows RNA is required for dynein activation.

This study investigates how DYNC1H1 mutations affect dynein motility and links these defects to neurological diseases.