Author

F. Beke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

C. Kapeni· 2 shared M. de la Roche· 2 shared A. Garcia-Gimenez· 1 shared A. Godsinia· 1 shared A. R. Fard· 1 shared B. Huntly· 1 shared C. Chilamakuri· 1 shared C. M. Sauer· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCell Biology

C. Kapeni

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

LGR5 targeting molecules as therapeutic agents for multiple cancer types

H.-C. Chen, N. Mueller, K. Stott, E. Rivers, C. Kapeni, C. M. Sauer, F. Beke, S. Walsh, N. Ashman, L. M. O'Brien, A. R. Fard, A. Godsinia, F. Joud, O. Giger, I. Zlobec, , M. de la Roche

This study develops LGR5-targeting antibodies and therapeutics that effectively kill CRC, HCC, and pre-B ALL cancer cells while sparing normal tissues.

bioRxiv · Sep 1, 2022 · PreprintCell Biology

Non-canonical Hedgehog signaling through L-type voltage gated Ca2+ channels controls CD8+ T cell killing

J. Hanna, C. Kapeni, L. O'Brien, V. Carbonaro, F. Beke, C. Chilamakuri, M. de la Roche

This study identifies L-type voltage gated Ca2+ channels as essential for Hedgehog signaling in CD8+ T cells, which is critical for their cytotoxic function.

bioRxiv · Mar 1, 2021 · PreprintImmunology