Author

N. Ashman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

A. Garcia-Gimenez· 1 shared A. Godsinia· 1 shared A. M. Santos· 1 shared A. R. Fard· 1 shared B. Huntly· 1 shared C. Eggeling· 1 shared C. Kapeni· 1 shared C. M. Sauer· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCell Biology

A. Garcia-Gimenez

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

LGR5 targeting molecules as therapeutic agents for multiple cancer types

H.-C. Chen, N. Mueller, K. Stott, E. Rivers, C. Kapeni, C. M. Sauer, F. Beke, S. Walsh, N. Ashman, L. M. O'Brien, A. R. Fard, A. Godsinia, F. Joud, O. Giger, I. Zlobec, , M. de la Roche

This study develops LGR5-targeting antibodies and therapeutics that effectively kill CRC, HCC, and pre-B ALL cancer cells while sparing normal tissues.

bioRxiv · Sep 1, 2022 · PreprintCell Biology

Aggregation and immobilisation of membrane proteins interplay with local lipid order in the plasma membrane of T cells

I. Urbancic, L. Schiffelers, E. Jenkins, W. Gong, A. M. Santos, F. Schneider, C. O'Brien-Ball, M. T. Vuong, N. Ashman, E. Sezgin, C. Eggeling

The paper investigates how membrane protein aggregation and immobilization affect lipid order in T cells, revealing lipid-mediated recruitment of signaling proteins like Lck.

bioRxiv · Dec 22, 2020Biophysics

Genetic dissection of a Leishmania flagellar proteome demonstrates requirement for directional motility in sand fly infections

T. Beneke, F. Demay, E. Hookway, N. Ashman, H. Jeffery, J. Smith, J. Valli, T. Becvar, J. Myskova, T. Lestinova, S. Shafiq, J. Sadlova, P. Volf, R. J. Wheeler, E. Gluenz

This study identifies flagellar proteins in Leishmania and shows that directional motility is essential for parasite colonization of sand flies.

bioRxiv · Nov 27, 2018Cell Biology